3,5-Dibromobenzeneboronic acid

3,5-Dibromobenzeneboronic acid - Names and Identifiers

Name	3,5-Dibromobenzeneboronic acid
Synonyms	AKOS BRN-0062 RARECHEM AH PB 0025 3,5-dibrombenzolboronsaeure 3,5-Dibromophenylboronic acid 3,5-DIBROMOPHENYLBORONIC ACID 3,5-DibroMobenzeneboronic Aicd 3,5-DIBROMOBENZENEBORONIC ACID 3,5-Dibromophenyl boronic acid 3,5-Dibromobenzeneboronic acid BORONIC ACID,B-(3,5-DIBROMOPHENYL)-
CAS	117695-55-3
EINECS	681-178-2
InChI	InChI=1/C6H5BBr2O2/c8-5-1-4(7(10)11)2-6(9)3-5/h1-3,10-11H
InChIKey	DKYRKAIKWFHQHM-UHFFFAOYSA-N

3,5-Dibromobenzeneboronic acid - Physico-chemical Properties

Molecular Formula	C6H5BBr2O2
Molar Mass	279.72
Density	2.09±0.1 g/cm3(Predicted)
Melting Point	>300 °C (lit.)
Boling Point	382.8±52.0 °C(Predicted)
Flash Point	185.3°C
Vapor Presure	1.52E-06mmHg at 25°C
Appearance	Powder
BRN	6645285
pKa	6.58±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.651
MDL	MFCD01075725
Use	Reactant involved in:Vacuo condensation and on-surface radical addition for synthesis of phenylene-boroxine networks;Lithiation of dihalophenyl dioxazaborocines yielding functionalized dihalophenylboronic acids;Cycloboronation of tetrasubstituted

3,5-Dibromobenzeneboronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29319090
Hazard Note	Irritant

3,5-Dibromobenzeneboronic acid - Introduction

3,5-Dibromobenzeneboronic acid is an organic compound whose chemical formula is C6H5BBr2O2. The following is a description of its nature, use, preparation and safety information:

Nature:
3,5-Dibromophenylboronic acid is a white solid that is stable at room temperature. Its melting point is 180-182 degrees Celsius. It is difficult to dissolve in water, but it can be well dissolved in organic solvents. It is a weak acid.

Use:
3,5-dibromophenylboronic acid has important application value in the field of organic synthesis. It can be used as catalyst and intermediate of organic synthesis reaction. For example, it can be used in the synthesis of phenylboronic esters, which play an important role in the Suzuki reaction. In addition, it can also be used in the synthesis of other organic compounds, such as drugs and dyes.

Preparation Method:
3,5-Dibromobenzeneboronic acid is typically prepared by reacting boric acid with 3,5-dibromobenzyl alcohol. The boric acid is first dissolved in a suitable solvent, then 3,5-dibromobenzyl alcohol is added and the reaction is stirred at an appropriate temperature. Finally, the product can be obtained by crystallization or extraction.

Safety Information:
3,5-dibromophenylboronic acid is generally relatively safe under normal use conditions, but the following matters still need to be paid attention:
1. should avoid contact with skin and eyes, avoid inhalation of dust or mist.
2. in use should take appropriate protective measures, such as wearing gloves, safety glasses and protective masks.
3. Keep away from flammable materials and oxidants, and operate in a well-ventilated place.
4. During use or storage, care should be taken to avoid contact with oxygen, acid or alkali to avoid dangerous reactions.
5. If accidental leakage or other accidents occur, corresponding emergency measures shall be taken immediately and professional personnel shall be consulted for handling.

Please note that the above information is for reference only. Please refer to the safety technical manual of the chemical or consult a professional for specific operations.

Last Update：2024-04-09 21:00:56